When a group of college students take part in a clinical drug trial, an unexpected side effect of the experimental medicine gives them terrifying visions of their own deaths...which begin to come true. As they scramble to escape their fate, they discover that the killer is among them and shares their ability to see the future - only he seems to be one step ahead of their efforts to survive.
Emily has just purchased a remote home near an institution to provide better care for her brother Zach who is crippled with a severe form of Cerebral Palsy. During their first evening the group discovers strange symbols etched into the boards on the windows. They begin to clear away the symbols in the effort to clean the house, but soon realize just how serious of a mistake that was. One by one the group of friends become possessed by the evil spirits that haunt the cabin causing chaos that will forever be scarred into the mind of whoever survives.